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Understanding neuronal cell biology: From development to diseases

Thursday, November 13, 2025

10:00 - 11:15 am

100 College Street
Floor 11, Workshop 1116

Neurons are large, complex cells with an extraordinarily long lifespan and require specialized mechanisms to accommodate their unique needs for morphogenesis, intracellular trafficking, and long-term homeostasis. The scarcity of knowledge in neuronal cell biology leads to major gaps in linking genetic variations to behavioral deficits in neurodevelopmental and neurodegenerative disorders.

The Shen Lab has established an in vivo system focusing on a systematic, mechanistic understanding of specialized neuronal cell biology using this highly polarized, highly arborized C. elegans neuron. Kang Shen will present recent and largely unpublished results on several topics in neuronal cell biology, including microtubule organization, neuronal stress response, and Tau toxicity. Shen will be hosted by Shaul Yogev.

Kang Shen

Professor of Biology; Director, Wu Tsai Neurosciences Institute, Stanford University

Shen is a neuronal cell biologist interested in development and maintenance of the nervous system.

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Kang Shen

WTI Inspiring Speaker Series

The Wu Tsai Institute's Inspiring Speaker Series features an interdisciplinary lineup of speakers whose work reshapes how we understand the mind and brain. Talks occur monthly on Thursdays at 10:00 am, from September 2025 to May 2026, at 100 College Street. Coffee and refreshments will be available before each talk, and there will be an opportunity for questions afterward. All members of the Yale community are welcome.

If you would like to meet with a visiting speaker, please contact wti@yale.edu.

Upcoming Speakers