Show all breadcrumbs Breadcrumb Janghoo Lim, PhD Faculty Member Center for Neurocognition and Behavior Email | Lab | Department | X | NCBI Methods animal models ; behavioral testing ; immunocytochemistry ; postmortem brain ; tissue culture ; transcriptomics Topics cellular neuroscience ; cerebellum ; genetics ; glia ; neurodegenerative diseases ; neurological disorders Research Contributions Differential effects of Wnt-β-catenin signaling in Purkinje cells and Bergmann glia in spinocerebellar ataxia type 1 PNAS (2022) Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1 bioRxiv (2021) Microglia regulate brain progranulin levels through the endocytosis-lysosomal pathway JCI Insight (2021) Molecular pathway analysis towards understanding tissue vulnerability in spinocerebellar ataxia type 1 eLife (2018) Polyglutamine disease toxicity is regulated by Nemo-like kinase in spinocerebellar ataxia type 1 Journal of Neuroscience (2013)