Neural cartography: Mapping the brain across scales
Aaron Kuan's lab investigates how circuit connectivity within and between brain areas supports a diverse array of functions. Kuan develops new electron microscopy and X-ray imaging techniques to enable 3D imaging of neuronal circuits with unprecedented resolution and scale and combines these approaches with behavior and functional imaging to reveal how circuit connectivity underlies brain activity and, ultimately, cognition. The long-term research goal is to extend high-resolution circuit mapping techniques to brain-wide scales to unite "top-down" and "bottom-up" views of brain anatomy and function.