Neuroimmune interactions and brain wiring
The Favuzzi Lab focuses on how neuroimmune interactions regulate brain wiring, function, and dysfunction. This includes understanding how microglia interact with neurons and synapses in health and disease. The lab addresses these questions using multi-level approaches that bridge molecular, cellular, and imaging techniques with behavior. Using mice as model organisms, they combine molecular approaches (e.g., spatial transcriptomics and single-cell multiomics), in vivo two-photon structural and functional imaging, and modern viral and transgenic tools.
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Biography
Emilia Favuzzi holds a BS in Biology and an MS in Neurobiology from Sapienza University of Rome. She completed her doctoral training in the lab of Beatriz Rico at the Institute of Neuroscience in Spain and the Centre for Developmental Neurobiology at King’s College London, where she focused on inhibitory circuit development. During her postdoctoral work in Gord Fishell’s laboratory at Harvard Medical School and the Broad Institute, Favuzzi discovered that specialized microglia differentially engage with specific synapse types. In 2022, she joined Yale as Assistant Professor of Neuroscience and Wu Tsai Investigator. In her free time, she enjoys painting, traveling, going on bike rides, visiting museums, and anything artsy.