Cellular metabolism
The long-term research interest in my laboratory is to study the "unknowns" in cellular metabolism. I will focus on characterizing human orphan metabolic enzymes and transporters genetically associated with neurological and psychiatric disorders. I plan to harness the power of modern technology, including CRISPR genome editing and high-resolution mass spec metabolomics, in my research at the interface between metabolic biochemistry and neuronal cell biology. Because cellular metabolism is central to neuronal development and intercellular communication in the developing brain, our research fits with the Neurodevelopment and Plasticity Center mission at the Wu Tsai Institute.