RNA regulation and dysregulation in the brain
Research in the Guo Lab aims to understand the roles of post-transcriptional gene regulation in the nervous system's development, functions, and diseases. Their work has identified mRNA translation control mechanisms that diversify the structures and functions of synaptic proteins and other fundamental building blocks of cognition and behaviors. They have also uncovered pathological mechanisms underlying several forms of age-dependent cognitive impairment, such as frontotemporal dementia.
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Biography
Junjie Guo received his PhD in Neuroscience from Johns Hopkins University and completed his postdoctoral training at the Whitehead Institute/MIT. He joined the Department of Neuroscience at Yale School of Medicine as an Assistant Professor in 2017 and currently serves as a Co-Director of the Graduate Studies of the Interdepartmental Neuroscience PhD Program (INP). Outside his lab, Junjie is a choir singer and table tennis enthusiast.