Yong-Hui Jiang, PhD

I am a physician scientist active both in basic research and clinical practice. My research interests are to 1) uncover the genetic and epigenetic bases of neurodevelopmental disorders or rare diseases with neurodevelopmental defects; 2) model genetic diseases using human patients derived cellular models and genetic mutant mice; 3) understand the circuit and molecular mechanisms underlying autism spectrum disorder; 4) develop novel molecular and epigenetic targeted therapies for genetic and epigenetic diseases with neurodevelopmental impairments. We use the genomic approach to discover the genetic defects in children with autism spectrum disorder and intellectual disability. Our ultimate goal is to develop effective treatment or intervention for individuals with autism and other neurodevelopmental disorders. The uniqueness and strength of my research programs are spanning human to model organisms, molecule genetics to physiology, and mechanism to treatment.

I received an MD from Shanghai Medical University (currently Shanghai Medical College of Fudan University), and my PhD in Molecular and Human Genetics from Baylor College of Medicine. I completed my pediatric residency and clinical genetic fellowship at Texas Children?s Hospital and Baylor College of Medicine. My research work focuses on understanding the mechanism and developing treatment of the genetic causing neurodevelopmental disorders in human and model organisms. I love to listen the classic music when I am working at home.